Exosomes are the latest breakthrough in regenerative aesthetics, often described as the "next generation" of skin rejuvenation beyond PRP and Polynucleotides. They are extracellular vesicles—microscopic messengers—that transmit signals between cells. In aesthetic medicine, exosomes are typically derived from stem cells and applied topically after treatments like microneedling or Morpheus8 to dramatically accelerate healing and stimulate collagen production.
Unlike PRP (which uses your own blood) or Polynucleotides (derived from salmon DNA), exosomes contain a highly concentrated, lab-purified mix of growth factors, peptides, amino acids, and vitamins. They act as "command centres," instructing older, sluggish skin cells to repair and behave like younger cells.
Exosomes are too large to penetrate intact skin, which is why they are almost always paired with a treatment that creates micro-channels in the skin (like microneedling, radiofrequency microneedling, or laser resurfacing). Once these channels are open, the exosome serum is applied and absorbs deeply into the dermis.
Once inside, they release billions of regenerative signals that:
An exosome treatment is an add-on procedure. You will first undergo your primary treatment (e.g., microneedling). Immediately following this, while the micro-channels in your skin are still open, the practitioner will apply the exosome serum. It feels cooling and soothing, providing instant relief from the heat or tingling of the primary procedure. There are no additional injections required for the exosome portion.
Exosomes are suitable for almost all skin types and ages. They are particularly beneficial for: